About this product

The Healthy Gut Girl EstroClear Smart Stack is an advanced estrogen metabolism and detox-support formula built around four core pathways: methylation, COMT-dependent clearance, liver/antioxidant defense, and gut-mediated elimination.

With Magnesium Glycinate, a 10 billion CFU multi-strain probiotic, Choline, NAC, Milk Thistle, Zinc Picolinate, Vitamin C, and Organic Broken Cell Chlorella, EstroClear is designed for women who want targeted support for healthy estrogen metabolite processing, methylation capacity, liver detox pathways, glutathione status, and gut balance.

Magnesium Glycinate supports COMT — the enzyme that helps methylate and neutralize reactive Phase I estrogen intermediates. Choline supports methylation capacity. The probiotic blend supports a balanced gut environment associated with healthy β-glucuronidase activity. NAC, Milk Thistle, Vitamin C, Zinc, and Chlorella round out antioxidant, liver, and green-detox support.

EstroClear is a more complete approach than piecing together single-ingredient bottles — designed to help you methylate, clear, defend, and eliminate.

Suggested use

Take one daily serving (one pack, 8 capsules) as directed on the label, preferably with food. EstroClear is best used consistently as part of a broader routine that supports digestion, elimination, adequate protein intake, hydration, and liver health.

Do not exceed the suggested serving unless directed by your healthcare provider.

About monthlees

The supplement industry is built on inflated pricing, confusing labels, and aggressive marketing.

Monthlees exists to fix that.

We believe:

  • Supplements should be clinically dosed
  • Pricing should be transparent
  • Testing should be independent
  • And customers shouldn't pay for influencer commissions or retail margins

Instead of hiding costs inside the product price, we use a simple membership model — so you pay what supplements actually cost to make.

Shipping & returns

• Shipping: Orders are processed within 1–2 business days. Standard delivery takes 3–7 business days depending on your location.
• Returns: You may return or exchange products within 30 days of receiving your order. Items must be in original condition with proof of purchase.
If your item is defective or damaged due to manufacturing issues, we’ll gladly replace it at no additional cost.

30 Day Money Back Guarantee

Your routine should feel simple, supportive, and worth it. If EstroClear is not a fit for you, contact support@monthlees.com within 30 days and we'll help make it right.

FDA Disclaimer

† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

EstroClear is intended for healthy adults seeking nutritional support for estrogen metabolite processing, methylation, liver detox pathways, glutathione status, gut balance, and antioxidant defense.

What's in EstroClear™ SmartStack™ Estrogen Clearance + Detox Support?

EstroClear combines Magnesium Glycinate for COMT-dependent clearance support with a 10 billion CFU multi-strain probiotic for gut balance, plus Choline for methylation, NAC for glutathione-related antioxidant defense, Milk Thistle for liver support, and Chlorella, Zinc, and Vitamin C for cellular and detox-pathway support.

Each 8-capsule serving is built to support the full estrogen-clearance story: methylate, clear, defend, and eliminate.

  • Magnesium Glycinate 133 mg for COMT-dependent clearance support
  • 10 billion CFU multi-strain probiotic for gut balance
  • Choline 420 mg for methylation support
  • NAC 600 mg for glutathione-related antioxidant defense
  • Milk Thistle extract standardized to 80% silymarin
  • Vitamin C 1,000 mg, Zinc Picolinate 25 mg, and Organic Broken Cell Chlorella 500 mg

Free of

  • Artificial colors
  • Artificial flavors
  • Added sugar
  • Hidden proprietary blends

Diet friendly

  • Daily hormone-support routines
  • Estrogen clearance support routines
  • Liver-support routines
  • Methylation-support routines
  • Healthy Gut Girl Smart Stack systems

Estrogen clearance beyond a single-ingredient approach

EstroClear was built to support the full estrogen-clearance story: methylation, COMT-dependent processing, gut balance, liver support, antioxidant defense, and elimination.

  • Magnesium Glycinate

    Magnesium Glycinate

    Supports COMT — the magnesium-dependent enzyme involved in methylating reactive estrogen intermediates. Included at 133 mg per serving.

  • 10B Probiotic

    10B Probiotic

    Multi-strain probiotic blend (10 billion CFU) with prebiotic fibers to support gut balance and healthy elimination.

  • Choline + NAC

    Choline + NAC

    Methylation and glutathione-related antioxidant defense — rounding out the processing and defense layers.

  • Milk Thistle + Chlorella

    Milk Thistle + Chlorella

    Liver and green-detox support for broader clearance and elimination.

How it works

  1. Methylate & clear

    Step 1: Methylate & clear

    Magnesium Glycinate supports COMT — helping the body methylate and neutralize reactive Phase I estrogen intermediates. Choline supports methylation capacity through one-carbon metabolism.

  2. Balance & eliminate

    Step 2: Balance & eliminate

    A 10 billion CFU multi-strain probiotic supports gut balance associated with healthy β-glucuronidase activity — supporting the elimination side of the clearance story.

  3. Defend

    Step 3: Defend

    NAC, Milk Thistle, Vitamin C, Zinc, and Chlorella support glutathione status, liver detox pathways, antioxidant defense, and natural clearance.

Supplement facts

COMT clearance, gut balance, methylation, and detox defense

EstroClear is organized into six systems: COMT-dependent clearance, gut balance, methylation support, glutathione/antioxidant defense, liver/green detox support, and mineral support.

Magnesium
Magnesium Glycinate
133 mg
† Daily Value not established.
Probiotic Blend
10 Billion CFU
L. acidophilus, L. rhamnosus, B. lactis, L. casei, L. brevis, L. paracasei, L. bulgaricus, L. salivarius, B. bifidum
Prebiotic fibers: inulin, fructooligosaccharides (FOS)
† Daily Value not established. Strain panel per label.
Choline
Choline Chloride
420 mg
† Daily Value not established.
N-Acetyl Cysteine
NAC
600 mg
Vitamin C
Ascorbic Acid
1,000 mg
1,111%
† Daily Value not established.
Milk Thistle Seed Extract
80% Silymarin
250 mg
Milk Thistle Seed
Silybum marianum
200 mg
Organic Broken Cell Chlorella
500 mg
† Daily Value not established.
Zinc
Zinc Picolinate
25 mg
227%
Percent Daily Value based on a 2,000 calorie diet.
Research-backed supplement formula visual
Evidence-based ingredients

The science behind the ingredients

EstroClear is built around research-supported pathways involved in estrogen metabolite processing, methylation, COMT-dependent clearance, gut balance, glutathione-related antioxidant defense, and liver support. Magnesium is a required cofactor for COMT activity. Specific probiotic strains have been studied for effects on β-glucuronidase activity in the gut. Choline supports methyl-donor pathways. NAC supports glutathione-related antioxidant defense. Milk Thistle is included for liver support with context-dependent human evidence.
8
Capsules per daily serving
133 mg
Magnesium Glycinate per serving
10B CFU
Probiotic blend per serving
NIH fact sheet Magnesium

Magnesium as an essential enzyme cofactor

NIH notes magnesium serves as a cofactor for more than 300 enzyme systems, including those involved in neuromuscular signaling and methylation-related pathways. COMT — involved in catechol estrogen processing — is magnesium-dependent.
Clinical research Probiotics

Lactobacillus and β-glucuronidase activity

Human and mechanistic research has examined how specific Lactobacillus and Bifidobacterium strains may influence β-glucuronidase activity in the gut — relevant to the elimination side of estrogen clearance, without making disease-treatment claims.
Mechanistic research NAC

NAC and reactive estrogen metabolite defense

Research on catechol estrogen quinones and estrogen-DNA adducts identifies N-acetylcysteine as a compound of interest for reducing formation of estrogen-DNA adducts. This supports an antioxidant defense angle, not a direct claim that NAC clears estrogen.
NIH fact sheet Choline

Choline as methylation support

NIH notes that choline needs rise when folate intake is low because choline can serve as an alternate methyl-donor pathway. This supports the formula's methylation-positioning for healthy estrogen metabolite processing.
Systematic review Milk Thistle / Silymarin

Silymarin and liver enzyme research

A systematic review suggests silymarin may have favorable effects on liver enzyme levels in some contexts, especially metabolic liver conditions, but findings are context-dependent. This supports cautious liver-support language rather than aggressive detox claims.

Compare EstroClear

How EstroClear stacks up against typical hormone-support formulas

Many hormone-support products focus on one pathway. EstroClear supports methylation, COMT-dependent clearance, gut balance, liver support, and antioxidant defense.
How EstroClear stacks up against typical hormone-support formulas
Typical single-pathway hormone product

Typical single-pathway hormone product

COMT + clearance support
Magnesium Glycinate 133 mg
Often not included
Gut balance + elimination
10 billion CFU multi-strain probiotic
Often not included
Methylation support
Includes Choline 420 mg
Often not included
Glutathione-related antioxidant defense
Includes NAC 600 mg + Vitamin C 1,000 mg
Often not included
Liver-support layer
Milk Thistle extract + whole seed
Often not included
Green detox support
Organic Broken Cell Chlorella 500 mg
Often not included
Formula philosophy
Methylate, clear, defend, eliminate
Usually single-pathway support

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Retailer markups
Middleman's cut
Cost of manufacture

What you'll pay at traditional retail

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What you'll pay as a guest

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Monthlees member

What you'll pay as a Monthlees member

The honest math on building an estrogen-support stack

To recreate EstroClear separately, you would typically need multiple products: Magnesium Glycinate, a multi-strain probiotic, Choline, NAC, Milk Thistle, Vitamin C, Zinc, and Chlorella. EstroClear puts the core stack into one streamlined daily system.
Half the cost
Treatment Other guys Monthlees
Typical separate-product stack Magnesium Glycinate + Probiotic + Choline + NAC + Milk Thistle + Vitamin C + Zinc + Chlorella purchased separately Multiple bottles / higher monthly cost One Smart Stack · 8 capsules
Monthlees member price Same EstroClear SKU with active member pricing Traditional retail anchor Member price shown at checkout

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Your membership gives you access to better pricing, personalized guidance, and everything you need to build a healthy supplement & personal care routine that effortlessly fits your life.

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From clear member pricing to flexible subscriptions and responsible product standards, Monthlees is built to help you shop with confidence — without inflated markups, hidden tiers, or checkout surprises.

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    Start, pause, skip, or adjust product subscriptions from your account — without hidden hoops or confusing rules.

Frequently asked questions

Everything you need to know about Monthlees member pricing, subscriptions, and how checkout works.

Why isn't DIM in EstroClear anymore?
We removed DIM based on expert feedback that it's best used as a standalone product with careful titration at lower doses. EstroClear now focuses on Magnesium Glycinate for COMT support, a 10 billion CFU probiotic for gut balance, and the methylation, liver, and antioxidant layers that round out the clearance story.
Why Magnesium Glycinate and a probiotic?
Magnesium supports COMT — the enzyme that helps methylate reactive estrogen intermediates. The probiotic blend supports gut balance associated with healthy β-glucuronidase activity, supporting the elimination side of clearance. Together they address different parts of the pathway DIM alone couldn't cover at a comfortable dose.
Can I take EstroClear while pregnant, nursing, or trying to conceive?
Do not use EstroClear during pregnancy, nursing, or while trying to conceive unless specifically directed by your healthcare provider. You should also consult your healthcare provider if you use hormone therapy, take medications, or have a hormone-sensitive condition.

Why I created monthlees...

When I was 19 years old, I was diagnosed with a brain tumor. That experience forced me to start asking deeper questions about how the human body actually works.

Over the next 18 months, I immersed myself in studying health, nutrition, and neuroscience — eventually earning my degree in Neuroscience from Duke University. Along the way, I discovered something powerful: the body is incredibly resilient & inherently self-healing when it’s given the right support.

Strategic nutrition and supplementation became a major part of my own health journey. And over the last two decades, I’ve devoted my life to helping millions of people around the world take a more proactive role in their health.

That experience completely changed how I thought about health — and ultimately shaped the way Monthlees was built.

I created Monthlees because I was tired of seeing people pay premium prices for supplements that were under-dosed, over-marketed, and difficult to trust.

My goal is simple: build the kind of brand I would want for myself and my family — with better ingredients, transparent formulas, meaningful dosages, and a business model built on long-term trust.

— Chris Walker, Founder of Monthlees

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